Some reports say D-mannose slows down this protein loss and makes your liver work better. It may also reduce bleeding disorders and low blood sugar in people with this disease. Preliminary clinical trials in Europe show that D-mannose may also treat or prevent urinary tract infections (UTIs).
 
D-mannose worked about as well as the antibiotic nitrofurantoin for preventing UTIs over a 6-month period. In a 2014 study, D-mannose was compared to the antibiotic trimethoprim/sulfamethoxazole for treatment and prevention of frequent UTIs in 60 women. D-mannose reduced UTI symptoms in women with an active infection.